Another study found that DMY also ameliorated hyperlipidemia and inhibited inflammation by reducing serum interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) mRNA expression, suppressing ROS generation and nicotinamide adenine dinucleotide phosphate (NADPH) oxidase 2 (NOX2), nuclear factor-κB (NF-κB), intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1) protein expression in aorta of LDLr−/− mice with HFD. The gene discussed is TNF; the disease is hyperlipidemia.