VEGFA and neoplasm: [14] The expression of some important angiogenic factors as the Vascular Endothelial Growth Factor (VEGF) subtypes and their receptors (VEGF-Rs), is upregulated on vascular endothelial cells during tumor angiogenesis and correlates with tumor growth rate, microvessel density, tumor proliferation, tumor metastatic potential and finally poorer patient prognosis.