The angiogenic factors sFLT1 and PGF play roles in angiogenesis, while LGALS13 is released from the syncytiotrophoblast and is involved in regulating the maternal blood pressure.[8,29,37] The results of this study showed normal sFLT1/PGF ratios in normal pregnancy and IUGR cases while there were higher values in late and early-onset preeclampsia. This evidence concerns the gene LGALS13 and preeclampsia.