However, testing for PD-L1 tumor expression is not a labeled requirement for use of nivolumab and atezolizumab, although FDA-approved drug-specific complementary PD-L1 diagnostic assays were developed for use in clinical trials, namely, the Agilent PD-L1 IHC 28–8 pharmDx for nivolumab and the Ventana PD-L1 (SP142) Assay (Ventana Medical Systems, Tucson, AZ) for atezolizumab [6–9]. Here, CD274 is linked to neoplasm.