Some studies have shown that lncRNA NEAT1 expression is increased in some cancers.10, 11, 12, 13 To verify the expression of NEAT1 in CRC tissues, we used 2015 TCGA sequencing data (https://genome-cancer.ucsc.edu/), which showed that NEAT1 expression was significantly upregulated in unpaired (n = 392) or paired CRC samples (n = 27) as compared to the normal tissues (n = 27) (Figure 1A). This evidence concerns the gene NEAT1 and cancer.