CD274 and clear cell renal carcinoma: The high expression of PD-L1 in clear cell renal carcinoma and non-clear cell renal carcinoma correlates with a poor prognosis.[11,12] However, the correlation between PD-L1 expression and the response rate to nivolumab is unclear.[13] Mizutani et al[8] reported that high PD-L1 expression in CDC contributes to a favorable clinical response to nivolumab, and the findings from our case study are in accordance with that study.