Histopathological RYR1-RM subtypes include central core disease (CCD) [10, 11], multiminicore disease (MmD) [12], centronuclear myopathy (CNM) [13], core–rod myopathy (CRM) [14], and congenital fiber-type disproportion (CFTD) [15]. This evidence concerns the gene RYR1 and centronuclear myopathy.