IFNG and colorectal carcinoma: A remarkably similar profile was observed amongst CRC patients, with the highest mean IFN-γ+ T cell response again being pool H, and the weakest mean response in pool F. Compared to CRC patients, higher percentages of 5T4-reactive healthy donors were observed for all the peptide pools (Fig. 1b), in line with previous observations from our laboratory examining responses to the 5T4 protein [15].