In this study, we assessed the mutational landscape and somatic mutation burden of the KRAS gene across 32 major primary cancer types and metastatic cancers with 33 different tissue origins using DNA-SEQ data from The Cancer Genome Atlas (TCGA) and Memorial Sloan Kettering Cancer Center Integrated Mutation Profiling of Actionable Cancer Targets (MSKCC-IMPACT) database. Here, KRAS is linked to metastatic malignant neoplasm.