In our study, we have found that there are significant differences in the expression of genes (SYK, PI3K, and EGFR) and the concentration of cytokines between dust mite-induced asthma and healthy controls, suggesting that EGFR, SYK, and PI3K may be involved in dust mite-induced pediatric asthma. The gene discussed is EGFR; the disease is childhood onset asthma.