TRIM5 and viral infectious disease: In the case of viral infections, PRRs, such as RIG-I and TLRs, and autophagy receptors tripartite motif containing 5 (TRIM5) and p62, can detect viral components and thereby induce selective autophagy against the sensed virus (Dong and Levine, 2013; Moy et al., 2014; Jackson, 2015; Galluzzi et al., 2017).