AGR2 and gastric adenocarcinoma: Additionally, elevated AGR2 protein expression is observed in numerous cancer types including gastric adenocarcinoma (19), breast (20), non-small cell lung (21), ovarian (22, 23), esophageal, prostate, and pancreatic cancer (24), and overexpression of the AGR2 protein is correlated with poor prognosis in these carcinomas.