Race, height, BMI, family history of cancer, physical examination in the past 2 years, history of colonoscopy or sigmoidoscopy, smoking, physical activity, alcohol intake, current multivitamin use, total energy intake, red and processed meat intake, folate intake, calcium intake, and Alternate Healthy Eating Index 2010 prostate-specific antigen test in the past 2 years. The gene discussed is KLK3; the disease is cancer.