Gene mutation of EGLN1, FH, KIF1B, MEN1, NF1, RET, SDHAF2, SDHC, SDHD, TMEM127, VHL, and SDHA was negative.<h4>Conclusion</h4>Whether paraganglioma/pheochromocytoma/PTC combination is coincidental or resulted from an underlying unknown mutation cannot be excluded. This evidence concerns the gene SDHAF2 and hereditary pheochromocytoma-paraganglioma.