Fgf10 gene mutations have been associated with diseases, such as aplasia of lacrimal and salivary glands (ALSG) (Entesarian et al., 2007) and lacrimo-auriculo-dento-digital (LADD) syndrome (Rohmann et al., 2006); chronic obstructive pulmonary disease (Klar et al., 2011) and certain cancer types, including breast (Theodorou et al., 2004; Ghoussaini et al., 2016), pancreatic (Nomura et al., 2008), and gastric (Sun et al., 2015) cancers (Figure 1C). This evidence concerns the gene FGF10 and cancer.