Similarly, SNPs affecting FGFR2b expression have been correlated with breast cancer susceptibility (Meyer et al., 2008; Fachal and Dunning, 2015) and amplification of FGFR1, occurring in up to 12% of breast cancer cases (Cerami et al., 2012; Gao et al., 2013; Pereira et al., 2016), is correlated with poor prognosis (Reis-Filho et al., 2006; Elbauomy Elsheikh et al., 2007). This evidence concerns the gene FGFR1 and breast carcinoma.