On the other hand, hRSV-infection has been associated with an early induction of Mcl-1 -another antiapoptotic factor that belongs to the Bcl-2 family- along with more antiapoptotic factors (Bcl-W, Bcl-xL) and pro-apoptotic factors (Bid, Bax, Bak), which all could be mediated by the NF-κB pathway (25), suggesting that hMPV could also be using others factor from the Bcl-2 family. This evidence concerns the gene BCL2 and infection.