Interestingly, it has been shown that Galectin-3 (GAL-3) is a ligand for oncofetal Thomson-Friedenreich carbohydrate (Galβ1, 3GalNAcα-, T, or TF) antigens on MUC1 mucin, which are expressed on human colon cancer cells (49). The gene discussed is LGALS3; the disease is malignant colon neoplasm.