Previous studies have shown that LMNA mutations causing skeletal muscle laminopathies lead to defects in nuclear shape in primary patient fibroblasts (Favreau et al., 2003; Muchir et al., 2003, 2004; Tan et al., 2015), murine C2C12 myoblasts (Favreau et al., 2003; Scharner et al., 2011; Barateau et al., 2017), as well as primary human myoblasts (Bertrand et al., 2014). The gene discussed is LMNA; the disease is laminopathy.