NRG1 and schizophrenia: Neuregulin 1 (NRG-1), a gene involved in regulating oligodendrocyte development and function is also implicated in schizophrenia (Papaleo et al., 2016; Mostaid et al., 2017) There is some evidence for neuroinflammation playing a role in schizophrenia as inflammatory mediators such as IL-10 as a promoter polymorphism in this gene has been shown to be a risk factor for schizophrenia development (He et al., 2006).