NOS2 and infection: This type of microglia is characterized by the production of NO by the iNOS, encoded by the Nos2 gene; (MacMicking et al., 1997; Arnold et al., 2014) and by the expression of inflammatory chemokines and cytokines, such as interleukin IL-6, IL-12, IL-1β, IL-23, and TNF-α that attract new cells of the immune system to the site of infection (Mosser and Edwards, 2008; Murray et al., 2014).