KCNMB2 and Menkes disease: However, as shown in Figure 3E, we only observed an increasing trend, but not a significant increase of fAHP in MD F1 pyramidal neurons overexpressing Kcnmb2. In addition, given the difference in the relative expression of Kcnmb2, we would expect that there is a significant difference in the half-width between CD-control and CD-Kcnmb2, also between MD-control and MD-Kcnmb2.