Additionally, a significant association was found between histological subtype and APC and SCGB3A1 methylation levels: special subtype carcinomas disclosed the lowest SCGB3A1 methylation levels in comparison to all the other histological subtypes (p = 0.016) and lower APC methylation levels comparing with invasive lobular carcinomas (p = 0.0293). The gene discussed is APC; the disease is invasive lobular breast carcinoma.