In order to confirm the association between P-cadherin and SRC activation, we started by analysing the expression of CDH3 (P-cadherin codifying gene) and SRC associated genes (SRC, YES1, FYN, LYN, LCK, CSK) in a public database of breast cancer cell lines belonging to different molecular subtypes (Fig. 1a) [CCLE database [20]]. This evidence concerns the gene LYN and breast carcinoma.