ERBB2 and neoplasm: We observed the greatest differences for the Basal-like, Her2-enriched and Normal breast-like subtypes whereas similar performance was achieved for Luminal A and Luminal B. In our simplified model with three tissue types for the TCGA dataset, we observed that the mean proportion value for the tumor component was lower (S1:μ = 0.48, σ = 0.08) compared to the mean estimated by histology (μ = 0.74, σ = 0.18).