Dereli-Korkut et al. [83] fabricated a 3D microfluidic cell array that mimicked a 3D microenvironment for tumor cancer cells as well as microvascular endothelial cells to simulate blood circulation to investigate the effect of the anticancer drugs such as Tarceva (Tar), Staurosporine (Sta), TNF-α with Cycloheximide (TNF-α/CHX) and Colchicine (Col) by encapsulating the human non-small cell lung cancer cell line (PC9) and adult human dermal blood microvascular endothelial cells (HMVEC) in 3D hydrogel (Figure 5). This evidence concerns the gene TNF and non-small cell lung carcinoma.