Koukourakis et al found that LDHA expression was positively associated with activation of the VEGF signaling pathway.62, 74, 75, 76 In studies on endometrial cancer, it was confirmed that LDHA expression was significantly related with the activation of vascular endothelial growth factor receptor 2 (VEGFR2) phosphorylation.74 High expression of LDHA was also strongly associated with VEGF expression in non‐small‐cell lung cancer.17 Activated VEGF/VEGFR2 signaling could remarkably promote angiogenesis. The gene discussed is LDHA; the disease is endometrial cancer.