CDH1 and cancer: Furthermore, activating epithelial‐to‐mesenchymal transition (EMT) also underlies LDHA contribution to cancer metastasis.73 In bladder cancer, Jiang et al73 found that knockdown of LDHA prevented invasion of cancer cells, accompanied by decreased Snail, N‐cadherin, fibronectin, and vimentin expression but increased E‐cadherin expression.