GZMK and neoplasm: The expression of LDHA in human melanoma is negatively correlated with the T‐cell activation markers such as granzyme K (GZMK) and CD25.84 The number of cytotoxic effector cells in tumors with low expression of LDHA was high compared to those with abundant LDHA.84 Husain et al85 observed a decrease in the number of myeloid‐derived suppressor cells (MDSCs) in the spleen of tumor‐bearing mice after depletion of LDHA.