Hepatocyte-nuclear factor 4 alpha (HNF4A), Translocase of outer mitochondrial membrane (TOMM34), and SRC protooncogene, nonreceptor tyrosine kinase (SRC) proteins encoded by the 20q chromosomal region, were highly affected by the 20q amplification event and may play a vital role in attaining the cancer hallmark of sustained proliferation [49]. Here, HNF4A is linked to cancer.