In the analysis using multivariate logistic regression model, gestational age at birth (OR = 0.93; 95% CI 0,9-0,96; p <0.001), neonatal HGB (OR = 0.77; 95% CI: 0.63-0.93; p = 0.007), and neonatal PLT (OR = 0.9912; 95% CI: 0,9857-0,9967; p = 0.002) were the risk factors of RDS in premature neonates (Table 2) (Figure 2). The gene discussed is CYGB; the disease is newborn respiratory distress syndrome.