Statins, known as 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMG-CoA reductase) inhibitors, are a class of lipid-lowering medications and represent a promising drug for the treatment of endometriosis because they have anti-proliferative, anti-angiogenic, antioxidant, and anti-inflammatory properties and can inhibit matrix metalloproteinase activity [46–48]. Here, HMGCR is linked to endometriosis.