Taking into account the different types of DM, Ebert et al. published one of the first articles associating gestational diabetes (GD) with irisin; among their main results, they showed that over pregnancy, there are no differences in irisin concentration in the groups of women with GD and healthy pregnant women; irisin was significantly higher in the group of women with GD. This evidence concerns the gene FNDC5 and diabetes mellitus.