A Milliplex 41-plex human cytokine/chemokine magnetic bead panel was used to measure changes in the release of 41 human cytokines, chemokines and growth factors in the culture medium of KFDV- or mock-infected HDMECs at 0, 24, 48 and 120 h p.i. This analysis provided further evidence that IL-6 expression and release is increased in response to KFDV infection (Fig. 1e). The gene discussed is IL6; the disease is infection.