There were high levels of leukocyte counts, platelet counts, albumin, triglyceride, and prothrombin activity and low ratio of neutrophil to lymphocyte and low levels of aspartate aminotransferase (AST), total bilirubin (TBIL), and γ-glutamyl transferase (GGT) in patients with HCC without cirrhosis (p < 0.0001). Here, F2 is linked to hepatocellular carcinoma.