It is noteworthy that, in our study, when restricting analysis to the patients without ongoing AKI at the time of CM infusion (n = 42), only a minority (n = 10, 24%) experienced a significant increase in [TIMP-2]·[IGFBP-7] (≥0.3) at 6 or 24 h after CM infusion. This evidence concerns the gene TIMP2 and acute kidney injury.