In univariate analyses, significant predictive factors for finding distant metastasis during surgery were younger age (p = 0.003), larger tumor size (p < 0.001), tumor location (p = 0.048), lower ALT level (p < 0.001), lower AST level (p = 0.006), lower TBil level (p < 0.019), higher CA199 level (p = 0.007), and higher CEA level (p < 0.001) (Table 3). The gene discussed is GPT; the disease is neoplasm.