The panel of chosen biomarkers expressed by T-cells included: [a] IL-2, important for downstream immune activation [b] TNF⍺, important in acute phase immune cell activation, differentiation and migration [c] IL-10, with the role of tumor-specific immune surveillance and mitigating pathologic inflammation, and [d] IFNγ, with the role of tumor- protection through immune cell activation including dendritic cells. This evidence concerns the gene IL10 and neoplasm.