TIL were expanded from primary (P) or metastatic lesions (ML) in medium containing IL-2, IL-15 and IL-21 from 2 patients with pancreatic cancer (PDAC), 1 patient with glioblastoma (GB), 1 patient with fibrosarcoma (FS) and 1 patient with uveal melanoma (UVM). The gene discussed is IL2; the disease is familial pancreatic carcinoma.