ERBB2 and neoplasm: The patient with a CR (HER2 IHC score 3+ and FISH HER2/CEP17 ratio 1.3) recurred with HER2 IHC score 0 and FISH HER2/CEP17 ratio 1.2 metastasis, and the patient with ovarian carcinosarcoma (HER2 IHC score 1+ and FISH HER2/CEP17 ratio 1.0) who had initial tumor shrinkage (-24.8%) progressed with new lesions showing HER2 IHC score 0 and FISH HER2/CEP17 ratio 1.2, suggesting immune escape.