We performed a pan-cancer correlation analysis between PAK4 expression and T-cell infiltration using TCGA expression data from 32 cancer types, identifying a negative correlation in melanoma (pcc = -0.31 and p-value= 7.4e-12), prostate cancer (pcc = -0.26 and p-value= 7.9e-09) and pancreatic cancer (pcc = -0.41 and p-value= 1.6e-08) among 20 other cancer types with similar negative correlation. Here, PAK4 is linked to cancer.