Cell sorting demonstrated that supra adventitial-adipose stromal cells (SA-ASC; CD235a-/CD45-/CD34+/CD146-/CD31-), and pericytes (CD235a-/CD45-/CD34-/CD146+/CD31-) were the two cell populations of SVF cells that were efficient facilitating the delivering of VACV to the tumor cells, validating their clinical use as a tool to potentiate oncolytic virus therapies in autologous settings. The gene discussed is GYPA; the disease is neoplasm.