Notably, despite having higher ICAM-1, we found that EWS-FLI1 ‘low’ cells are actually less susceptible to T-cell mediated apoptosis that EWS-FLI1 ‘high’ cells, suggesting that EWS-FLI1 ‘low’ cells possess an ability to evade T-cell- mediated tumor killing. The gene discussed is ICAM1; the disease is neoplasm.