qPCR confirmed the expression of GNRHR/Gnrhr (Fig. 2A and C) and LHCGR/Lhcgr (Fig. 2B and D) in the normal human and mouse adrenals, adrenocortical tumors and H295R, Cα1, Y-1 cell lines (except Lhcgr in Y-1). Here, CA1 is linked to adrenal cortex neoplasm.