PDX1 and diabetes mellitus: We therefore examined the effect ofexposure to glucose concentrations often found in diabetic humans (20 mM/360 mg/dL).Adult pdx-1 mutant zebrafish which develop diabetes have mean bloodglucose levels of 219 mg/dL (12 mM), while streptozotocin-induced pancreatic damageraises blood glucose levels in adult zebrafish to similar levels to diabetic humans.38 Although no study has successfully measured blood glucose in zebrafish larvaeor embryos, these data suggest our study examined the effect of a relevant level ofglucose exposure.