Over the past year, manylaboratories have described the important role played by PON2 in tumor cells.Hence, they have demonstrated that PON2 contributes to the progression andmetastasizing of pancreatic cancer by stimulating glucose uptake [8], accelerates the proliferation of andresistance to oxidative stress in bladder cancer [9], protects glioblastoma cells against apoptosis [10], and reduces the sensitivity of oralcancer cells to radiation therapy [11].However, the exact role played by PON2 in other cancer types is yet to beelucidated. This evidence concerns the gene PON2 and cancer.