BDNF and major depressive disorder: In addition, a decreased BDNF level was detected in thehippocampus of patients with depression and in suicide victims [6, 7].The pathogenetic role of BDNF in depression has been demonstrated to beassociated with the regulation of neuroplasticity and neurogenesis in thehippocampus [8], impairment of which isconsidered to be the leading etiopathogenetic factor of the disease [9].