The results of our study contradict those of Emingil et al15 and Fokkema et al.16 Emingil et al15 reported that subjects with generalized aggressive periodontitis and those with chronic periodontitis have similar MIP-1α and MIP-1β levels in GCF samples when compared with gingivitis and periodontal healthy subjects. The gene discussed is CCL3; the disease is gingivitis.