The ability of gingival epithelial cells to produce MIP-1α may provide a sustained source of this chemo-kine, thereby modulating the host response to inflammation in the gingival sulcus and in the surrounding gingival epithelium.12 Another chemokine, MIP-1β, also called CCL4, is considered to be appreciably expressed chemokine in periodontitis. The gene discussed is CCL4; the disease is periodontitis.