A statistical significant difference (p < 0.001) was observed for each of APPL2, AMD1, LTC4S, OAT, NKX3.1, ALDH1A3, and TPD52 (p ≤ 0.05) when PCa of AA-origin compared to PCa of CA-origin cells as shown in Fig. 2. This evidence concerns the gene APPL2 and posterior cortical atrophy.