Our results showed that these genes are involved in multiple pathways of cancer, prostate cancer, focal adhesion, lipid metabolism, constitutive PI3K/AKT signaling, EGFR, PDGF, FGFR, ERBB2/DAP12 and MAPK signaling pathways (depicted in Table S3). The gene discussed is ERBB2; the disease is Familial prostate cancer.