First, CD14+CD11b+CD33+ monocytic cells expressing low levels of HLA-DR (HLA-DRlo) and resembling one of the most established human MDSC-like phenotype [11] as previously described by us in chronic lymphocytic leukemia (CLL) and malignant melanoma [10, 12] were quantified in the peripheral blood of patients with newly diagnosed AML. This evidence concerns the gene CD14 and B-cell chronic lymphocytic leukemia.