For example, lncRNA HOTAIR was upregulated in OSCC tumour tissues and OSCC cell lines; moreover, overexpression of HOTAIR enhanced the metastatic potential and epithelial‐mesenchymal transition (EMT) characteristics of OSCC.21 LncRNA CEBPA‐AS1 is up‐regulated in OSCC and functions as a potential oncogene, being correlated with poor differentiation, lymph node metastasis and high clinical stage via a novel pathway CEBPA/Bcl2.22 Here, HOTAIR is linked to neoplasm.