LEF1 and astrocytoma (excluding glioblastoma): Although 52.9% (9/17) and 41.2% (7/17) of total astrocytomas showed strong and moderate expression levels of LEF1 and TCF1, respectively, there was no correlation to methylation profile or to SFRP1 expression: LEF1 and methylation (Spearman’s rho = 0.079; P = 0.781), TCF1 and methylation (Spearman’s rho = -0.084; P = 0.766), LEF1 and SFRP1 expression (Spearman’s rho = 0.046; P = 0.867), TCF1 and SFRP1 expression (Spearman’s rho = 0.211; P = 0.433).