When we compared the dental arch dimensions of patients with Saethre-Chotzen syndrome or TCF12-related craniosynostosis, we found that the dental arch dimensions in Saethre-Chotzen syndrome or TCF12-related craniosynostosis patients were also statistically significantly smaller than those of the control group, except for the mandibular IMW and for the AD in both jaws. Here, TCF12 is linked to craniosynostosis.