As shown in Table 2, univariate analysis showed that MYO18B expression (HR = 2.993, P = 0.002), pathologic-stage (HR = 3.708, p < 0.001) and pathologic-T (HR = 3.783, P < 0.001) were obviously related to overall survival in HCC, while age, gender, grade, pathologic-M and pathologic-N showed no significant association with overall survival (P > 0.05). Here, MYO18B is linked to hepatocellular carcinoma.