Monocyte subset TLR-4 expression analysis revealed no significant differences at baseline or after LPS treatment in classical (CD14+/CD16-) or intermediate (CD14+/CD16+) subpopulations between children with DS and controls (Fig. 3c (p = 0.51), d (p = 0.4) and Fig. 5c (p = 0.75), d (p = 0.84)). This evidence concerns the gene TLR4 and Dravet syndrome.