In addition, the positive correlation between miR-15a and miR-16-1 in the Men1+/− mouse pituitary tumours (Fig. 1) indicates that these miRNAs are likely transcribed as a polycistronic cluster, under the control of the same promoter elements, as reported for these miRNAs in patients with chronic lymphocytic leukaemia (CLL) (Calin et al. 2008). The gene discussed is MEN1; the disease is pituitary tumor.